Advanced Milk Thistle-1925

Advanced Milk Thistle-1925

$34.50
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120 Softgels | Gluten free | Non-GMO

Liver health formulas made with milk thistle have been in use for centuries. Advanced milk thistle extract contains phytonutrients that fight oxidative stress and support liver health. Combining silybin with phosphatidylcholine and other phospholipids enhances the absorption of milk thistle's active compounds, providing powerful liver health support.

Milk thistle compounds support liver health and phospholipids promote their absorption for enhanced health support.

Advanced Milk Thistle Benefits

Delivers standardized nutrients to promote liver health & function

Supports the body’s natural detoxification process

Encourages healthy cell division within the liver

Enhances absorption of active compounds into the bloodstream

Milk Thistle for Liver Health

Milk thistle contains powerful compounds that are beneficial not only for the liver, but for the overall health and vitality of the entire body. But the active compound in milk thistle, silybin, does not dissolve well in water, making it difficult for the body to absorb. Our milk thistle formula overcomes this roadblock by mixing silybin with a nutrient called phosphatidylcholine to boost uptake.

Healthy liver, healthy body

Modern living puts a heavy load on the liver, making it critical to proactively maintain liver health. That’s where hepato-protective herbs such as milk thistle come in. Milk thistle contains antioxidants that support not only liver health, but overall health.1-3

Silymarin is extracted from milk thistle. This extract is a powerful free radical scavenger that promotes healthy liver function in its own right.4-10 Advanced extraction technology has now allowed us to isolate other constituents within the silymarin extract itself and test their ability to support liver health and beyond.

Other compounds in our milk thistle extract

Silibinin is another compound present in our high-quality milk thistle extract. Made up of silybins A and B, it is the most biologically active flavonolignan component found in milk thistle extract. Its beneficial effects on the liver have been shown in pre-clinical and clinical studies.8,11 Other milk thistle extracts called isosilybin A and B have proven to be the most efficient at helping to maintaining healthy cell division.12,13

Phosphatidylcholine and other phospholipids enhance milk thistle’s delivery

The main bioactive compound of milk thistle, called silybin, does not dissolve well in water.14 This makes it difficult for the body to absorb all of it.14,15 Scientists have overcome silybin’s poor bioavailability by integrating it into a phytosome. A phytosome is a tiny sphere made out of plant-derived phosphatidylcholine.

This phosphatidylcholine-based delivery system facilitates transportation across the intestinal lining into the bloodstream, making it an ideal carrier molecule for silybin.8,15,16 Scientists believe that phosphatidylcholine molecularly bonds to silybin, helping to steer it through the cell membranes in the intestinal tract.15 This improves the delivery of the benefits of milk thistle extracts for liver health.

Preclinical and clinical evidence showed that this silybin-phosphatidylcholine complex resulted in almost 5-fold greater concentrations of silybin in the bloodstream than silymarin alone, and its ultimate bioavailability to the liver, its target organ, is up to 10-fold greater than pure silymarin.17-19

Dosage and Use
  • Take two (2) softgels daily, in divided doses, or as recommended by a healthcare practitioner.
Warnings
  • KEEP OUT OF REACH OF CHILDREN
  • DO NOT EXCEED RECOMMENDED DOSE
  • Do not purchase if outer seal is broken or damaged.
  • When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
  1. Pharmacogn Rev. 2016;10(19):66-70.
  2. Evid Based Complement Alternat Med. 2015;2015:536564.
  3. Global J Dig Dis. 2018;4(2:3):1-4.
  4. Phytotherapy Research. 2010;24(10):1423-1432.
  5. Phytomedicine. 2009;16(5):391-400.
  6. Antioxidants (Basel). 2015;4(1):204-47.
  7. World J Hepatol. 2014;6(3):144-9.
  8. World J Gastroenterol. 2011;17(18):2288-301.
  9. Molecules. 2017;22(2):E191.
  10. Medicine (Baltimore). 2017;96(49):e9061.
  11. Int J Clin Exp Med. 2015;8(3):4320-7.
  12. Int J Cancer. 2008;123(1):41-50.
  13. Carcinogenesis. 2007;28(7):1533-42.
  14. Altern Med Rev. 2005;10(3):193-203.
  15. Altern Med Rev. 2009;14(3):226-46.
  16. Nat Struct Biol. 2002;9(7):507-11.
  17. Eur J Drug Metab Pharmacokinet. 1990;15(4):333-8.
  18. Eur J Drug Metab Pharmacokinet. 1992;17(1):39-44.
  19. Eur J Drug Metab Pharmacokinet. 1993;18(3):289-97.
 
 
 

 

 

 

 
 
 

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